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Описание

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Адвантан крем д/нар.прим., 0.1%, 15 г

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Коротко о товаре

Артикул Маркета
4314842372
Тип препарата
Назначение
Действующее вещество
Возраст
от 4 месяцев
Инструкция
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Взрослым и детям с 4-х месячного возраста. Препарат наносят 1 раз в сутки тонким слоем на пораженные участки кожи. Как правило, длительность непрерывного ежедневного лечения Адвантаном не должна превышать 12 недель для взрослых и 4-х недель для детей. При подостром и остром воспалении без выраженного мокнутия требуется лекарственная форма с небольшим содержанием жира и высоким содержанием воды. Крем Адвантан обеспечивает устранение воспалительного процесса и на гладкой коже, и на волосистой части головы, в том числе, на коже, склонной к жирности."},{"name":"Побочные действия","value":"Обычно препарат хорошо переносится. Очень редко (менее чем в 0,01% случаев) могут наблюдаться местные реакции, такие как зуд, жжение, эритема, образование везикулёзной сыпи. Если препарат применяют более 4-х недель и/или на площади 10% и более поверхности тела, могут возникнуть следующие реакции: атрофия кожи, телеангиэктазии, стрии, акнеформные изменения кожи, системные эффекты, обусловленные абсорбцией кортикостероида. В ходе клинических исследований ни один из вышеперечисленных побочных эффектов не был отмечен при применении жирной мази Адвантан до 12 недель у взрослых и до 4-х недель у детей. В редких случаях (0,01% - 0,1%) может наблюдаться фолликулит, гипертрихоз, периоральный дерматит, депигментация кожи, аллергические реакции на один из компонентов препарата."},{"name":"Фармакологическое действие","value":"При наружном применении Адвантан подавляет воспалительные и аллергические кожные реакции, также как и реакции, связанные с усиленной пролиферацией, что приводит к уменьшению объективных симптомов воспаления (в т.ч. эритема, отек, мокнутие и т. д.) и субъективных ощущений (в т.ч. зуд, раздражение, боль и т. д.).\u003Cbr\u003EПри применении метилпреднизолона ацепоната наружно в рекомендуемой дозе системное действие выражено минимально как у человека, так и у животных. После многократного нанесения Адвантана на большие поверхности (40-60% поверхности кожи), а также при применении под окклюзионную повязку не отмечается нарушений функций надпочечников: уровень кортизола в плазме крови и его циркадный ритм остаются в пределах нормы, снижения уровня кортизола в суточной моче не происходит.\u003Cbr\u003EВ ходе клинических исследований при применении Адвантана до 12 недель у взрослых и до 4 недель у детей (в т.ч. раннего возраста) не было выявлено развития атрофии кожи, телеангиэктазий, стрий и угреподобных высыпаний.\u003Cbr\u003EМетилпреднизолона ацепонат (особенно его основной метаболит – 6α-метилпреднизолон-17-пропионат) связывается с внутриклеточными глюкокортикоидными рецепторами. Стероид-рецепторный комплекс связывается с определенными участками ДНК клеток иммунного ответа, таким образом, вызывая серию биологических эффектов.\u003Cbr\u003EВ частности, связывание стероид-рецепторного комплекса с ДНК клеток иммунного ответа приводит к индукции синтеза макрокортина. Макрокортин ингибирует высвобождение арахидоновой кислоты и, тем самым, образование медиаторов воспаления типа простагландинов и лейкотриенов.\u003Cbr\u003EИнгибирование ГКС синтеза вазодилатирующих простагландинов и потенцирование сосудосуживающего действия адреналина приводит к вазоконстрикторному эффекту."},{"name":"Фармакологическая группа","value":"глюкокортикостероид для местного применения"},{"name":"Форма выпуска","value":"крем"},{"name":"Способ применения/введения","value":"наружный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["35947170:36763741"]}}},{"name":"Минимальный возраст применения","value":"от 4 месяцев"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25°C. Срок годности – 3 года. Препарат следует хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При изучении острой токсичности метилпреднизолона ацепоната не было выявлено какого-либо риска острой интоксикации при чрезмерном однократном наружном применении (нанесение препарата на большую площадь при условиях, благоприятных для абсорбции) или непреднамеренном приеме внутрь.\u003Cbr\u003EСимптомы: при чрезмерно долгом и/или интенсивном местном применении ГКС может развиться атрофия кожи (истончение кожи, телеангиэктазии, стрии).\u003Cbr\u003EПри проявлении атрофии препарат необходимо отменить."},{"name":"Применение при беременности и кормлении грудью","value":"При необходимости применения мази (жирной) Адвантан во время беременности и лактации следует тщательно взвешивать потенциальный риск для плода и ожидаемую пользу лечения для матери. В эти периоды не рекомендуется длительное применение препарата на обширных поверхностях кожи. Кормящим матерям не следует наносить препарат на молочные железы."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Не выявлено."},{"name":"Особые указания","value":"При наличии бактериальных осложнений и/или дерматомикозов в дополнение к терапии Адвантаном необходимо проводить специфическое антибактериальное и/или антимикотическое лечение. Следует избегать попадания препарата в глаза. Как и в случае применения системных глюкокортикостероидов, после наружного применения глюкокортикостероидов может развиться глаукома (например, при применении больших доз, или очень длительного применения окклюзионных повязок или нанесения на кожу вокруг глаз)."},{"name":"Взаимодействие","value":"Не выявлено."},{"name":"Регистрационный номер","value":"П N013563/01"},{"name":"Дата государственной регистрации","value":"23.07.2020"},{"name":"Владелец регистрационного удостоверения","value":"Bayer","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["34324371:35649313","7893318:10965778"]}}},{"name":"Изготовитель","value":"Bayer"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Адвантан","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["17796364:17878939"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"2505150587300880193":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"кожа"},{"name":"Назначение","value":"аллергический дерматит, атопический дерматит, контактный дерматит, экзема"},{"name":"Показания к применению","value":"Атопический дерматит, истинная экзема, микробная экзема, аллергический и простой контактный дерматит, профессиональная экзема, дисгидротическая экзема."},{"name":"Противопоказания","value":"Гиперчувствительность, туберкулез, сифилис и вирусные инфекции кожи, розацеа, периоральный дерматит, участки кожи с реакцией на вакцинацию, детский возраст до 4 месяцев."},{"name":"Состав","value":"Действующее вещество: метилпреднизолона ацепонат – 1 мг\u003Cbr\u003EВспомогательные вещества: децилолеат – 100 мг, глицерил моностеарат 40-55% – 85 мг, цетостеариловый спирт (цетиловый спирт 60%, стеариловый спирт 40%) – 25 мг, жир твердый – 25 мг, софтизан 378 – 75 мг, макрогола стеарат – 30 мг, глицерол 85% – 50 мг, динатрия эдетат – 1 мг, бензиловый спирт – 10 мг, бутилгидрокситолуол – 60 мкг, вода очищенная – 597.94 мг\u003Cbr/\u003E"},{"name":"Действующее вещество","value":"Метилпреднизолона ацепонат"},{"name":"Способ применения и дозы","value":"Наружно. 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Если препарат применяют более 4-х недель и/или на площади 10% и более поверхности тела, могут возникнуть следующие реакции: атрофия кожи, телеангиэктазии, стрии, акнеформные изменения кожи, системные эффекты, обусловленные абсорбцией кортикостероида. В ходе клинических исследований ни один из вышеперечисленных побочных эффектов не был отмечен при применении жирной мази Адвантан до 12 недель у взрослых и до 4-х недель у детей. В редких случаях (0,01% - 0,1%) может наблюдаться фолликулит, гипертрихоз, периоральный дерматит, депигментация кожи, аллергические реакции на один из компонентов препарата."},{"name":"Фармакологическое действие","value":"При наружном применении Адвантан подавляет воспалительные и аллергические кожные реакции, также как и реакции, связанные с усиленной пролиферацией, что приводит к уменьшению объективных симптомов воспаления (в т.ч. эритема, отек, мокнутие и т. д.) и субъективных ощущений (в т.ч. зуд, раздражение, боль и т. д.).\u003Cbr\u003EПри применении метилпреднизолона ацепоната наружно в рекомендуемой дозе системное действие выражено минимально как у человека, так и у животных. После многократного нанесения Адвантана на большие поверхности (40-60% поверхности кожи), а также при применении под окклюзионную повязку не отмечается нарушений функций надпочечников: уровень кортизола в плазме крови и его циркадный ритм остаются в пределах нормы, снижения уровня кортизола в суточной моче не происходит.\u003Cbr\u003EВ ходе клинических исследований при применении Адвантана до 12 недель у взрослых и до 4 недель у детей (в т.ч. раннего возраста) не было выявлено развития атрофии кожи, телеангиэктазий, стрий и угреподобных высыпаний.\u003Cbr\u003EМетилпреднизолона ацепонат (особенно его основной метаболит – 6α-метилпреднизолон-17-пропионат) связывается с внутриклеточными глюкокортикоидными рецепторами. Стероид-рецепторный комплекс связывается с определенными участками ДНК клеток иммунного ответа, таким образом, вызывая серию биологических эффектов.\u003Cbr\u003EВ частности, связывание стероид-рецепторного комплекса с ДНК клеток иммунного ответа приводит к индукции синтеза макрокортина. Макрокортин ингибирует высвобождение арахидоновой кислоты и, тем самым, образование медиаторов воспаления типа простагландинов и лейкотриенов.\u003Cbr\u003EИнгибирование ГКС синтеза вазодилатирующих простагландинов и потенцирование сосудосуживающего действия адреналина приводит к вазоконстрикторному эффекту."},{"name":"Фармакологическая группа","value":"глюкокортикостероид для местного применения"},{"name":"Форма выпуска","value":"крем"},{"name":"Способ применения/введения","value":"наружный"},{"name":"Минимальный возраст применения","value":"от 4 месяцев"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25°C. Срок годности – 3 года. Препарат следует хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При изучении острой токсичности метилпреднизолона ацепоната не было выявлено какого-либо риска острой интоксикации при чрезмерном однократном наружном применении (нанесение препарата на большую площадь при условиях, благоприятных для абсорбции) или непреднамеренном приеме внутрь.\u003Cbr\u003EСимптомы: при чрезмерно долгом и/или интенсивном местном применении ГКС может развиться атрофия кожи (истончение кожи, телеангиэктазии, стрии).\u003Cbr\u003EПри проявлении атрофии препарат необходимо отменить."},{"name":"Применение при беременности и кормлении грудью","value":"При необходимости применения мази (жирной) Адвантан во время беременности и лактации следует тщательно взвешивать потенциальный риск для плода и ожидаемую пользу лечения для матери. В эти периоды не рекомендуется длительное применение препарата на обширных поверхностях кожи. Кормящим матерям не следует наносить препарат на молочные железы."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Не выявлено."},{"name":"Особые указания","value":"При наличии бактериальных осложнений и/или дерматомикозов в дополнение к терапии Адвантаном необходимо проводить специфическое антибактериальное и/или антимикотическое лечение. Следует избегать попадания препарата в глаза. Как и в случае применения системных глюкокортикостероидов, после наружного применения глюкокортикостероидов может развиться глаукома (например, при применении больших доз, или очень длительного применения окклюзионных повязок или нанесения на кожу вокруг глаз)."},{"name":"Взаимодействие","value":"Не выявлено."},{"name":"Регистрационный номер","value":"П N013563/01"},{"name":"Дата государственной регистрации","value":"23.07.2020"},{"name":"Владелец регистрационного удостоверения","value":"Bayer"},{"name":"Изготовитель","value":"Bayer"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Адвантан"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_6"}}}}
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Цена с картой Яндекс Пэй:711 ₽

Скидка: 1%
–1 %
Вместо: 718 ₽
  • 25 мая, курьер Маркета • 99 ₽
Яндекс
Рейтинг 4.9 из 5
17Котзывов
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Цена с картой Яндекс Пэй:830 ₽

Скидка: 2%
–2 %
Вместо: 846 ₽
  • 26 мая, курьер Маркета • 99 ₽
POLZAru
Рейтинг 4.9 из 5
37Котзывов
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Ещё может подойти

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Инструкция

Показания к применению

Атопический дерматит, истинная экзема, микробная экзема, аллергический и простой контактный дерматит, профессиональная экзема, дисгидротическая экзема.

Противопоказания

Гиперчувствительность, туберкулез, сифилис и вирусные инфекции кожи, розацеа, периоральный дерматит, участки кожи с реакцией на вакцинацию, детский возраст до 4 месяцев.

Способ применения и дозы

Наружно. Взрослым и детям с 4-х месячного возраста. Препарат наносят 1 раз в сутки тонким слоем на пораженные участки кожи. Как правило, длительность непрерывного ежедневного лечения Адвантаном не должна превышать 12 недель для взрослых и 4-х недель для детей. При подостром и остром воспалении без выраженного мокнутия требуется лекарственная форма с небольшим содержанием жира и высоким содержанием воды. Крем Адвантан обеспечивает устранение воспалительного процесса и на гладкой коже, и на волосистой части головы, в том числе, на коже, склонной к жирности.
Полная инструкция
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Адвантан крем д/нар.прим.
Адвантан крем д/нар.прим., 0.1%, 15 г
4.9
(25)
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1 вопрос
Инструкция

Цена с картой Яндекс Пэй:711 ₽

Скидка: 1%
–1 %
Вместо: 718 ₽
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4.9
У этого продавца: 25 оценок
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user avatar
23 ноября 2023 • Татьяна Пляцидевская
Достоинства: быстро заживляет. У меня аллергия на влажную и холодную погоду, кожа и на руках, и на ногах трескается и покрывается прыщиками. То...Недостатки: маленький тюбик
user avatar
15 мая • GLiana
Достоинства: Хороший крем, после первого применения виден результат👌🏼
user avatar
4 апреля • Наталья
Достоинства: быстро помог от атопического дерматитаНедостатки: нетКомментарий: рекомендую
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20 января • vladislav
Достоинства: ОтличноНедостатки: нетКомментарий: Помогло
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24 октября 2023 • Татьяна солнышко 🌞
Достоинства: помогает
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  • Адвантан мазь, 0.1%, 15 мл, 15 г
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    Адвантан мазь, 0.1%, 15 мл, 15 г

    Цена 659 ₽ вместо 740
  • Адвантан эмульсия д/нар. прим., 0.1%, 20 г
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    Адвантан эмульсия д/нар. прим., 0.1%, 20 г

    Цена 717 ₽ вместо 724
  • Адвантан мазь жирная, 0.1%, 15 г
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    Адвантан мазь жирная, 0.1%, 15 г

    Цена 714 ₽ вместо 721
  • Адвантан мазь д/нар. прим., 0.1%, 50 мл
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    Адвантан мазь д/нар. прим., 0.1%, 50 мл

    Цена 1 484 ₽ вместо 1 499
  • Адвантан крем, 0.1%, 15 мл, 15 г
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    Адвантан крем, 0.1%, 15 мл, 15 г

    Цена 750 ₽ вместо 902
  • Акридерм мазь д/нар. прим., 0.05%, 15 г
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    Акридерм мазь д/нар. прим., 0.05%, 15 г

    Цена 105 ₽ вместо 106
  • Комфодерм К крем д/нар. прим., 0.1%, 15 г
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    Комфодерм К крем д/нар. прим., 0.1%, 15 г

    Цена 588 ₽ вместо 594
  • Акридерм крем д/нар. прим., 0.05%, 30 г
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    Акридерм крем д/нар. прим., 0.05%, 30 г

    Цена 173 ₽ вместо 207
  • Реклама
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  • Комфодерм мазь д/нар. прим., 0.1%, 15 г
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    Комфодерм мазь д/нар. прим., 0.1%, 15 г

    Цена 483 ₽ вместо 581
  • Акридерм ГК мазь д/нар. прим., 15 г
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    Акридерм ГК мазь д/нар. прим., 15 г

    Цена 932 ₽ вместо 950
  • Тридерм крем, 15 г
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    Тридерм крем, 15 г

    Цена 1 092 ₽ вместо 1 103
  • Акридерм ГК крем д/нар. прим, 15 г
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    Акридерм ГК крем д/нар. прим, 15 г

    Цена 932 ₽ вместо 950
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 2 025 ₽ вместо 3 500
  • Низорал шампунь, 2%, 120 мл, 1 шт.
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    Низорал шампунь, 2%, 120 мл, 1 шт.

    Цена 1 065 ₽ вместо 1 076
  • Жидкий пластырь Fixplast c пантенолом, 60 мл
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    Жидкий пластырь Fixplast c пантенолом, 60 мл

    Цена 297 ₽ вместо 399
  • Хило-комод р-р увлажняющий офтальмологический конт., 1 мг/мл, 10 мл, 1 шт.
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    Хило-комод р-р увлажняющий офтальмологический конт., 1 мг/мл, 10 мл, 1 шт.

    Цена 744 ₽ вместо 910
  • Йодомарин таб., 0.1 мг, 100 шт.
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    Йодомарин таб., 0.1 мг, 100 шт.

    Цена 135 ₽ вместо 159
  • Вобэнзим таб. п/о кш/раств., 40 шт.
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    Вобэнзим таб. п/о кш/раств., 40 шт.

    Цена 712 ₽ вместо 719
  • Нафтизин капли наз. фл.-кап., 0.1%, 15 мл
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    Нафтизин капли наз. фл.-кап., 0.1%, 15 мл

    Цена 175 ₽ вместо 179
  • Магне B6 таб. п/о, 60 шт.
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    Магне B6 таб. п/о, 60 шт.

    Цена 659 ₽ вместо 666
  • Реклама
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  • Хлоргексидин биглюконат 2% раствор для дезинфекции, антисептик нестерильный с распылителем, 200 мл
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    Хлоргексидин биглюконат 2% раствор для дезинфекции, антисептик нестерильный с распылителем, 200 мл

    Цена 258 ₽ вместо 910
  • Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт
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    Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт

    Цена 197 ₽ вместо 250
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